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FV

Description

FV (G1691A) Leiden Mutation

Intended Use

Venous thrombosis is among the three most common cardiovascular diseases, affecting about 1 in 1000 individuals each year. Thrombotic risk is determined both by circumstancial factors (age, surgery, pregnancy, oral contraception), as well as by genetic predisposition. While the majority of known genetic defects within the blood coagulation cascade (protein S, protein C, antithrombin III) is rare, a G>A mutation at nucleotide position 1691 in the gene for coagulation factor V (FV Leiden) is found at high frequency (20- 60%) in thrombosis patients.



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Copyright © 2009 - 2019 İnvitrotek A.Ş. All Right Reserved by Invitrotek
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